mindblowingscience:

Researchers eliminate HIV from cultured human cells for first time

HIV-1, the most common type of the virus that causes AIDS,has proved to be tenacious, inserting its genome permanently into its victims’ DNA, forcing patients to take a lifelong drug regimen to control the virus and prevent a fresh attack. Now, a team of Temple University School of Medicine researchers has designed a way to snip out the integrated HIV-1 genes for good.

"This is one important step on the path toward a permanent cure for AIDS," says Kamel Khalili, PhD, Professor and Chair of the Department of Neuroscience at Temple. Khalili and his colleague, Wenhui Hu, MD, PhD, Associate Professor of Neuroscience at Temple, led the work which marks the first successful attempt to eliminate latent HIV-1 virus from human cells. "It’s an exciting discovery, but it’s not yet ready to go into the clinic. It’s a proof of concept that we’re moving in the right direction," added Dr. Khalili, who is also Director of the Center for Neurovirology and Director of the Comprehensive NeuroAIDS Center at Temple.
In a study published July 21 by theProceedings of the National Academy of Sciences, Khalili and colleagues detail how they created molecular tools to delete the HIV-1 proviral DNA. When deployed, a combination of a DNA-snipping enzyme called a nuclease and a targeting strand of RNA called a guide RNA (gRNA) hunt down the viral genome and excise the HIV-1 DNA. From there, the cell’s gene repair machinery takes over, soldering the loose ends of the genome back together — resulting in virus-free cells.
"Since HIV-1 is never cleared by the immune system, removal of the virus is required in order to cure the disease," says Khalili, whose research focuses on the neuropathogenesis of viral infections. The same technique could theoretically be used against a variety of viruses, he says.



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mindblowingscience:

Researchers eliminate HIV from cultured human cells for first time

HIV-1, the most common type of the virus that causes AIDS,has proved to be tenacious, inserting its genome permanently into its victims’ DNA, forcing patients to take a lifelong drug regimen to control the virus and prevent a fresh attack. Now, a team of Temple University School of Medicine researchers has designed a way to snip out the integrated HIV-1 genes for good.

"This is one important step on the path toward a permanent cure for AIDS," says Kamel Khalili, PhD, Professor and Chair of the Department of Neuroscience at Temple. Khalili and his colleague, Wenhui Hu, MD, PhD, Associate Professor of Neuroscience at Temple, led the work which marks the first successful attempt to eliminate latent HIV-1 virus from human cells. "It’s an exciting discovery, but it’s not yet ready to go into the clinic. It’s a proof of concept that we’re moving in the right direction," added Dr. Khalili, who is also Director of the Center for Neurovirology and Director of the Comprehensive NeuroAIDS Center at Temple.

In a study published July 21 by theProceedings of the National Academy of Sciences, Khalili and colleagues detail how they created molecular tools to delete the HIV-1 proviral DNA. When deployed, a combination of a DNA-snipping enzyme called a nuclease and a targeting strand of RNA called a guide RNA (gRNA) hunt down the viral genome and excise the HIV-1 DNA. From there, the cell’s gene repair machinery takes over, soldering the loose ends of the genome back together — resulting in virus-free cells.

"Since HIV-1 is never cleared by the immune system, removal of the virus is required in order to cure the disease," says Khalili, whose research focuses on the neuropathogenesis of viral infections. The same technique could theoretically be used against a variety of viruses, he says.

skeleton-on-the-internet:

redwhiteandblueliberty2:

actualjustice:

blastortoise:

Y’all can understand why the mutants in x-men hate the humans but can’t get why black people hate whites

Excuse me if I’m wrong, but aren’t the heroes the mutants who desire coexistence with humans, and the villains are extremist mutants who are so angry at their oppressors that they vilify and attack them?

OP person who doesn’t really know X-men.

blastortoise confirmed for rekt.

he’s saying the mutants in the x-men universe, not in the x-men themselves.
context~

titytwochainz:

wzrdkelley:

milliondollarnigga:

wzrdkelley:

what’s the appeal of her wearing heels while yall have sex? what does it do for you?

makes her seem like more of the whore she is, what hoe you know takes her shoes off when you paying for the action???

okay what if she’s not a whore?

she cosplaying a hoe for her nigga

my nigga Jalen knows whats good

(Source: naldouze)

wzrdkelley:

what’s the appeal of her wearing heels while yall have sex? what does it do for you?

makes her seem like more of the whore she is, what hoe you know takes her shoes off when you paying for the action???

were you able to record?

I actually haven’t, I been too busy to do that, but I’m gonna give it some trial runs tomorrow in the car, for sure.

Am I holding you up?

severalbadpunslater:

severalbadpunslater:

The marines better watch out cause here come the Primary Color Kids!

The Navy’s response is swift and merciless



Look at my nigga Glint Money Kizaru Borsalino

severalbadpunslater:

severalbadpunslater:

The marines better watch out cause here come the Primary Color Kids!

The Navy’s response is swift and merciless

Look at my nigga Glint Money Kizaru Borsalino

Here for it

Here for it

(Source: the-elle-word)

ikilledthecameraman:

tell me who do you think you are?

Baby daddy

ikilledthecameraman:

tell me who do you think you are?

Baby daddy

solarselection:

arctic-sea:

OH MY GOD SO

SO

I FOUND THIS BLOG WITH LIKE

A FUCKTON OF DEIDARA BUT 

BUT

THE PERSON WHO RUNS THE BLOG ALSO REBLOGS PICS OF DUDES THAT LOOK LIKE DIFF. VERSIONS OF DEIDARA

AND LOOK

WHAT I FUCKING FOUND

image

bruh

If he puts his hair in a ponytail he’d be Deidara, cannot unsee